2a edición. — Elsevier, 2014. — 264 p. Enfoque orientado a la comprensión de los conceptos fundamentales mediante la resolución de problemas. Cada capítulo comienza con un repaso teórico de esquemas y ecuaciones, seguido de problemas resueltos paso a paso. Nueva estructura en cinco secciones con cinco capítulos nuevos. Amplio equipo de colaboradores, integrado por profesores e...
Published by AvE4EvA 2015. — 166 p. ISBN10: 953-51-2197-9. ISBN13: 978-953-51-2197-8. This book considers the basic principles of biopharmaceutics and pharmacokinetics. The book illustrates clinical pharmacokinetic applications, such as recirculatory models, common antimalarial drugs, and clinical pharmacokinetic principles in critically ill patients, which are essential for...
Wiley, 2025. — 471 p. — ISBN-13 : 978-1394251285 In Basics and Clinical Applications of Drug Disposition in Special Populations, a team of distinguished researchers delivers a timely and authoritative discussion of how to predict drug disposition in special populations, including people with obesity, pediatric patients, geriatric patients, and patients with renal and hepatic...
Wiley, 2012. — 744 p. A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in...
3rd edition. — McGraw-Hill Education / Medical, 2014. — 1317 p. — ISBN: 978-0-07-179458-9. The most current, hands-on book in the field, Applied Clinical Pharmacokinetics The perfect textbook for pharmacy students learning the clinical application of pharmacokinetics, which is the mathematical tools for modifying doages. Students like that each chapter includes sample problems...
McGraw-Hill Education, 2008. — 826 p. The easiest and most trusted way to learn the clinical application of pharmacokinetics. "This is an important reference that teaches clinically relevant pharmacokinetic dosing and therapeutic drug monitoring tools. This second edition includes updated information on dosing immunosuppressants, as well as dosing concepts in pediatric and...
2nd Edition. — Springer, 2011. — 639 p. This is a second edition to the original published by Springer in 2006. The comprehensive volume takes a textbook approach systematically developing the field by starting from linear models and then moving up to generalized linear and non-linear mixed effects models. Since the first edition was published the field has grown considerably...
Springer Science + Business Media, 2006. — 512 p. Drug discovery and development is a very complex, costly, and ti- consuming process. Because of the uncertainties associated with predicting the pharmacological effects and the toxicity characteristics of new chemical entities in man, their clinical development is quite prone to failure. In recent years, phar- ceutical companies...
CRC Press, 2023. — 780 p. The main contribution of the principles of pharmacokinetics and toxicokinetics is to summarize the large quantity of observations in simple mathematical relationships, which then facilitate extrapolation and projection beyond the observations.
Taylor & Francis Group, 2015. — 538 p. Pharmacokinetics and Toxicokinetics provides an overview of pharmacokinetics and toxicokinetics in a comprehensible, interrelated, and applied manner. It integrates the principles held in common by both fields through a logical and systematic approach. The book presents mathematical descriptions of physiological processes employed in...
Springer, 2024. — 254 p. — ISBN-13 : 978-9819727759 The book provides a comprehensive exploration of the dynamic field of pharmacology and its fundamental principles. It delves into the intricate interactions between drugs and the human body, focusing on pharmacokinetics, which explains the dynamics of drug actions in the body, and pharmacodynamics, which uncovers the...
John Wiley & Sons, Ltd, 2005. - 274 p. ISBN: 0-470-86352-8. Drug metabolism is a core area of pharmacology. Before any drug can be licensed it is essential to know how the body metabolises the drug, and the short and long-term effects it has on the body. It is an area of rapid advancement, which brings together the fields of pharmacy, pharmacology and medicine. This new text...
3rd edition. — Wiley-Blackwell, 2020. — 671 p. — ISBN: 978-1-119-45856-2. The third edition of this comprehensive book covers basic concepts of teaching drug metabolism, starting from extreme clinical consequences to systems and mechanisms and toxicity. It provides an invaluable introduction to the core areas of pharmacology and examines recent progress and advances in this...
Editorial de la Universidad Nacional de La Plata (EDULP), 2017. — 214 p. Este libro aúna la experiencia docente y de investigación de los autores, que además de enseñar Farmacología ejercemos tareas de tiempo completo en distintos ámbitos de aplicación, como son tres diversos laboratorios de investigación de la Facultad de Ciencias Exactas de UNLP, dos centros de investigación...
Wiley, 2011. - 371 p. This is an authoritative, comprehensive book on the fate of drug molecules in the body, including implications for pharmacological and clinical effects. The text provides a unique, balanced approach, examining the specific physical and biological factors affecting the absorption, distribution, metabolism and excretion of drugs, together with mathematical...
2nd edition. — Wiley, 2023. — 480 p. — ISBN 9781119588436. In this new, fully-revised edition of Drug Disposition and Pharmacokinetics: Principles and Applications for Medicine, Toxicology and Biotechnology the authors deliver an authoritative and comprehensive discussion of the fate of drug molecules in the body, as well as its implications for pharmacological and clinical...
Wiley, 2017. — 338 p. The application of knowledge of drug disposition, and skills in pharmacokinetics, are crucial to the development of new drugs and to a better understanding of how to achieve maximum benefit from existing ones. The book takes the reader from basic concepts to a point where those who wish to will be able to perform pharmacokinetic calculations and be ready...
American Society of Health-System Pharmacists, 2005. — 230 p. The 15 lessons in this pharmacy textbook define the time course of drug absorption and metabolism in the human body, examine the relationship between drug concentration at the site of action and the resulting effect, and present brief patient case studies with aminoglycosides, theophylline, vancomycin, digoxin, and...
ITexLi, 2021. — 94 p. — ISBN 1839688793 9781839688799 1839688815 9781839688812. This book’s purpose is to provide some understanding of the biology and current technology applied in the field of drug metabolism. Drug metabolism comprises the identification, characterization, and quantification of the chemicals or compounds produced in an animal or human upon administration of a...
New York: Informa Healthcare USA, 2007. — 181 p. — ISBN13: 978-1-4200-6103-1, ISBN10: 1-4200-6103-8. In order to understand drug metabolism at its most fundamental level, pharmaceutical scientists must be able to analyze drug compound structures and predict possible metabolic pathways in order to avoid the risk of adverse reactions that lead to the withdrawal of a drug from the...
CRC Press, 2004. — 385 p. Руководство по биоанализу и метаболизму лекарств в организме человека. The importance of the physicochemical properties of drugs to drug metabolism Sample preparation High-performance liquid chromatography in pharmaceutical bioanalysis Mass spectrometry and quantitative bioanalysis Immunoassay in pharmacokinetic and pharmacodynamic bioanalysis...
Academic Press, 2020. — 340 p. — ISBN: 978-0-12-818596-4. This book presents foundational principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic principles, classical physiological models, the application of physiological models for dose-response and risk assessment, the use of in vitro...
Swedish Pharmaceutical Press, 2017. — 1057 p. Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications teaches everyday biological data analysis to the undergraduate and graduate levels. Through numerous examples and over 100 tutorials, scientists learn how to use PK/PD seamlessly in a variety of practical areas, from simple plasma kinetics,...
Springer, 2024. — 402 p. The book delves into the intricate realm of pharmacokinetics and pharmacodynamics as they apply to modern advancements in drug delivery systems. It offers a comprehensive exploration of novel drug delivery methods, with a particular focus on nanoparticles and nanocarriers. The absorption, distribution, metabolism, and excretion processes of...
Randy Glasbergen, 2005. — 236 p.
Substrates can undergo a broad range of reactions during metabolism.
These reactions include, for example, oxidation, reduction, hydrolysis, hydration, conjugation and condensation.
Drug metabolism is divided into 2 Phases -Phase I which are the functionalizationreactions;
And Phase II, which are the conjugation reactions.
New York: Springer, 2014. — 737 p. The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain...
3rd edition. — Routledge, 2024. — 464 p. — SBN 978-0-367-75214-9. This book introduces basic pharmacokinetic concepts to beginner learners to help them understand the absorption, distribution, metabolism, and excretion of drugs. After a basic introduction to pharmacokinetics and its related fields, the book provides a clear introduction to quantitative pharmacokinetic relations...
John Wiley & Sons Ltd , 2001. – 566 p.
Toxicology is now considered to be a topic worthy of study and research in its own right, having originally arisen as a subsection of pharmacology. This rapid growth in the significance of toxicology necessitates specialised yet comprehensive information that is easily accessible both to professionals and to the increasing number of students...
Springer, 2005. — 431 p. — ISBN: 978-1-4020-4141-9. Drug Metabolism: Current Concepts provides a comprehensive understanding of the processes that take place following ingestion of a medicinal agent or xenobiotic, with an emphasis on the crucial role of metabolism (biotransformation). How a sound knowledge of these phenomena is incorporated into the design of effective new drug...
2nd edition. — Pharmaceutical Press, 2012. — 492 p. — ISBN: 978-0-85369-980-4 Basic Pharmacokinetics provides an understanding of the principles of pharmacokinetics and biopharmaceutics. It addresses clearly and concisely how these principles can be applied to achieve successful drug therapy. The applications of principles and equations are illustrated with related problem sets...
Springer, 2016. — 597 p. This book is a comprehensive resource on psychotropic medications, detailing the latest methods for defining their characteristics, their use in different patient populations, and drug-drug interactions; an important collection of information forclinicians, students, researchers, and members of the pharmaceutical industry alike. The first section provides...
Elsevier Inc., 2011. — 370 p. Kar’s Essentials of Biopharmaceutics and Pharmacokinetics deals with how a drug exerts its action in the human body through the fundamentals of absorption, distribution, metabolism and excretion. The book adopts a growth-oriented format and design that is developed systematically and methodically. The book interrelates five different sections:...
Adis, 2015. — 149 p. This comprehensive review provides a systematic, unbiased analysis, critique and summary of the available literature and generates novel clinical decision-making algorithms which can aid clinicians and scientists in practice management and research development. Potential mechanisms for the identified drug interactions are deduced from available preclinical and...
Wiley, 2014. — 538 p. — ISBN: 978-3-527-67299-8 (Methods and Principles in Medicinal Chemistry). The authors provide more than a systematic overview of computational tools and knowledge bases for drug metabolism research and their underlying principles. They aim to convey their expert knowledge distilled from many years of experience in the field. In addition to the...
Kluwer, 2002. — 302 p. Bioneer Life Science, San Diego, CA. Designed for industrial scientists, laboratory assistants, and managers involved in PK/PD.DM-related areas. Each chapter deals with a particular issue and its industrial applications. Expanded-outline format. Pharmacokinetic Study Design and Data Interpretation. NewApproaches for HighThroughput In Vivo...
Academic Press, 2015. — 175 p. Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product...
2nd Edition. — Springer, 2016. — 497 p. The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into...
New York: Springer, 2006. - 444p. The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first...
Springer, 2023. — 208 p. — (AAPS Introductions in the Pharmaceutical Sciences ). — ISBN 978-3-031-29540-9. This book provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food...
Springer, 2016. — 512 p. — (AAPS Advances in the Pharmaceutical Sciences Series 23). — ISBN: 978-3-319-44532-8. While systems biology and pharmacodynamics have evolved in parallel, there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new discipline that is the interface...
Springer, 2024. — 168 p. Foreword Preface Acknowledgements Editors and Contributors About the Editors Contributors Abbreviations Introduction to Clinical Pharmacokinetics Inhibition of Biliary Excretion Pharmaceutical Drug Interactions Therapeutic Drug Monitoring Effect of Renal and Hepatic Diseases on Pharmacokinetics Individualization of Drug Dosage Correlation of...
Wiley, 2006. — 411 p. This first ever coverage of the pharmacokinetic and pharmacodynamic characteristics of biopharmaceuticals meets the need for a comprehensive book in this field. It spans all topics from lead identification right up to final–stage clinical trials. Following an introduction to the role of PK and PD in the development of biotech drugs, the book goes on to...
Springer, 2022. — 354 p. This textbook covers all the essential elements of pharmacokinetics, from basics to applications. It describes authoritative equations and methods on pharmacokinetic evaluation procedures with their importance. Each chapter of the book is supplemented with numerous illustrations and figures for easy understanding of the subject. The book presents...
Bentham Science Publishers, 2013. — 223 p. The endocannabinoid system comprises at least two G-protein-coupled receptors (the cannabinoid CB1 and CB2 receptors) activated by marijuana’s psychoactive principle ∆9-tetrahydrocannabinol (THC) and the endogenous ligands known as endocannabinoids. The apex of endocannabinoid research seems to have been reached with the clinical...
Bethesda: American Society of Health-System Pharmacists, 2017. — 481 p. Pharmacokinetic studies have continued to be published since the first edition of the Clinical Pharmacokinetics. The second, third, fourth, fifth and now sixth edition authors have taken advantage of advances in understanding to update the chapters. In many cases more judicious monitoring of drug...
Nightingale C.H. Antimicrobial pharmacodynamics in theory and clinical practice, Marcel Dekker, 2002, 427 p. The book includes a thorough discussion of the pharmacodynamics of all major classes of the antimicrobial armamentarium. These include penicillins, cephalosporins, cephamycins, carbapenems, monobactams, aminoglycosides, quinolones, macrolides, antifungals, antivirals and...
InTech, 2012. - 388 p. - This book covers up to date information and practical topics related to the study of drug pharmacokinetics in humans and in animals. The book is designed to offer scientists, clinicians and researchers a choice to logically build their knowledge in pharmacokinetics from basic concepts to advanced applications. This book is organized into two sections....
SEEd Medical Publishers, 2012. — 112 p.
In a period characterized by the gradual increase in life expectancy thanks to the availability of appropriate drug therapies for the treatment of many chronic diseases, it becomes essential to know how to properly handle the dosing regimens of drugs in relation to the patient's comorbidities and polytherapies. In this regard, knowledge...
Second Edition. — Informa Healthcare, 2008. — 616 p. This timely, expanded new edition is the definitive handbook for experienced drug metabolism and pharmaceutical scientists and those new to the field. Written by internationally renowned authors, it provides integrated, comprehensive coverage of fundamental aspects of drug metabolism and the practical applications that help...
3rd ed. — CRC Press, 2019. — 735 p. — ISBN: 978-1-4822-6203-2. This book continues to be the definitive reference on drug metabolism with an emphasis on new scientific and regulatory developments. It has been updated based on developments that have occurred in the last 5 years, with new chapters on large molecules disposition, stereo-selectivity in drug metabolism, drug...
Wiley, 2012. — 435 p. — ISBN: 978-0470484067 The only book dedicated to physiologically-based pharmacokinetic modeling in pharmaceutical science.Physiologically-based pharmacokinetic (PBPK) modeling has become increasingly widespread within the pharmaceutical industry over the last decade, but without one dedicated book that provides the information researchers need to learn...
Kluwer Academic Publishers, 2004. — 245 p. This book is divided into two parts; in the first part the principles and the methods of pharmacokinetics are described in detail, while in the second the main pharmacokinetic parameters are described, giving for each of them the definition, the principal properties, and the methods of determination. An appendix contains the important...
2nd Edition. - Wiley, 2011. - 443 p. - Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed yet practical manner.
Developed as a tool for ensuring that pharmacokinetics studies are properly designed and correctly interpreted, the book...
2nd Edition. — John Wiley & Sons, Inc, 2017. — 588 p. — ISBN10: 1119143152 Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and pharmacodynamics. It also features interactive computer simulations for students to experiment and observe PK/PD models in action. Presents the essentials of...
Wiley, 2011. — 450 p. With its clear, straightforward presentation, this text enables you to grasp all the fundamental concepts of pharmacokinetics and pharmacodynamics. This will allow you to understand the time course of drug response and dosing regimen design. Clinical models for concentration and response are described and built from the basic concepts presented in earlier...
Humana Press, 2016. — 661 p. This text offers state of the art contributions written by world renown experts which provide an extensive background on specific classes of antibiotics and summarize our understanding as to how these antibiotics might be optimally used in a clinical situation. The book explores pharmacodynamics methods for anti-infective agents, pharmacodynamics of...
Ventus Publishing ApS, 2012. — 147 p. All the basic concepts of pharmacokinetics (PKs) are described, with an emphasis on understanding what parameters such as bioavailability, volume of distribution and clearance tell us about the behaviour of a particular drug. The use of PKs in both a drug development and a clinical setting are covered. The essential mathematical basis of...
Bookboon, 2012. — 147 p. — ISBN: 978-87-403-0090-1 ntroduction ADME and Pharmacokinetics Absorption: Absorption rate constant, Bioavailability and Salt factor Distribution: Compartments and Volume of Distribution Elimination: Elimination rate constant, half-life and clearance Single intravenous bolus injection into one compartment Analysis of experimental data from a bolus i.v....
4th edition. — Wolters Kluwer, 2011. — 1267 p. Formerly Clinical Pharmacokinetics: Concepts and Applications, this fully updated Fourth Edition has been retitled Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications to reflect the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug...
3rd edition. — Lippincott Williams & Wilkins, 1995. — 616 p. — ISBN: 978-0683074048 Since pharmacokinetics can greatly affect how different patients respond to the same drug, both students and physicians need a basic clinical understanding of this vital area. The Third Edition of Clinical Pharmacokinetics provides a practical perspective, with these added features...
ITexLi, 2024. — 112 p. — ISBN 0850141486 9780850141481 0850141478 9780850141474 0850141494 9780850141498. This book delivers the latest information on biotransformation and other pharmacokinetic parameters required to assess drug safety in drug discovery and development. Drug metabolism and pharmacokinetics (DMPK) is considered a rational strategy for the design, optimization,...
2., unveranderte Auflage. — Stuttgart: Wissenschaftliche Verlagsgesellschaft, 2015. — XII, 147 S. — ISBN 978-3-8047-3476-0. Mit 52 Abbildungen, 25 Tabellen und 323 mathematischen Formeln. Das Schicksal der Arzneistoffe Dies ist eine Einführung in die Pharmakokinetik mit Schwerpunkt auf kinetischen Modellen und mathematischen Berechnungen. Behandelt werden u.a.: Grundlagen von...
Boca Raton: CRC Press, 2001. — 271 p. This book has evolved over the last twenty years from a cumulative effort to develop a professional course in pharmacokinetics that would assist future practitioners in therapeutic decision making. As practicing pharmacists become more involved with patient advising, it becomes apparent that clinicians will be required to make dosing...
New York: McGraw-Hill, 2015. — 929 p. The landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics--now fully updated. Explains how to detect clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Helps you critically evaluate biopharmaceutic studies involving drug product equivalency and...
6th ed. — ASHP, 2014. — 296 p.
Concepts in Clinical Pharmacokinetics has helped thousands of students and practitioners through five editions by simplifying a complex subject. The authors have thoroughly reviewed, revised, and redesigned the text to enhance the reader's grasp of the material. This 6th Edition offers a superior approach to understanding pharmacokinetics through...
Academic Press, 2022. — 805 p. — (Advances in Pharmaceutical Product Development and Research). — ISBN 978-0-323-98367-9. Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series,...
Hoboken: Wiley, 2007. — 643 p. In this age of combinatorial chemistry and high-throughput technologies, bioactive compounds called hits are discovered by the thousands. However, the road that leads from hits to lead compounds and then to pharmacokinetically optimized clinical and drug candidates is very long indeed. As a result, the screening, design, and optimization of...
Boston: Wolters Kluwer, 2016. - 401 p.
This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug...
Lippincott Williams, 2006. - 338 p. This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug...
Wiley, 2003. — 597 p. The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect. The efficacy of drug uptake depends on the one hand on the chemical characteristics of the active substance, above all on its solubility and membrane permeability. On the other hand, it is determined by the...
2nd ed. Completely Revised Edition. — Wiley, 2009. — 652 p.
The gold standard for industrial research now completely revised in line with current trends in the field, with all contributions extensively updated or rewritten.
In 21 chapters readers can benefit from the key working knowledge of today's leading pharmaceutical companies, including Pfizer, AstraZeneca, and Roche....
Springer, 2014. — 467 p. Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of...
Elsevier, 2018. — 127 p. — ISBN: 978-0-12-814595-1. Detection of Drugs and Their Metabolites in Oral Fluid presents the analytical chemistry methods used for the detection and quantification of drugs and their metabolites in human oral fluid. The authors summarize the state of the science, including its strengths, weaknesses, unmet methodological needs, and cutting-edge trends....
New York: Springer, 2020. — 254 p. This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book's contents. The rhythmic expression of...
Springer, 2020. — 646 p. — ISBN: 978-981-15-8807-5. This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book's contents. The...
Academic Press, 2017. — 282 p. Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism during these different pathophysiological states.Each chapter clearly...
Moscow: Peoples' Friendship University of Russia, 2019. — 56 p. — ISBN: 978-5-209-08937-7. The Tutorial Guide is a complete manual on the independent study of Pharmacodynamics by students of medical universities studying in English in the following specialties: 310501 “General Medicine”, 310503 “Dentistry” and 330501 “Pharmacy” corresponding to the federal state educational...
М.: Литтерра, 2005. - 288 с. - (Рациональная фармакотерапия). Книга посвящена практическим аспектам клинической фармакологии лекарственных средств и современным принципам рациональной фармакотерапии. На базе большого фактического материала обобщены основные принципы рационального выбора, применения и дозирования лекарств, анализа побочных эффектов. Особое внимание уделено...
Учебное пособие. — Оренбург: ОГУ, 2021. — 94 с. В пособие представлено краткое теоретическое изложение материала, а также вопросы для самоподготовки, фонды тестовых заданий, перечень вопросов выносимых на итоговое контрольное занятие, перечень рекомендуемой литературы по изучаемой дисциплине. Учебное пособие предназначено для самостоятельной работы обучающихся по специальности...
Ростов-на-Дону, "Феникс", 2001, 384 с. В учебнике освящаются особенности проведения фармакокинетических расчетов, фармакокинетические процессы, приводятся типы фармакокинетических моделей и т. д.
М.: Реафарм, 2004. — 144 с. Монография предназначена для фармакологов, клинических фармакологов, фармакокинетиков, научных работников, занимающихся изучением метаболизма лекарственных препаратов, аспирантов, а также для студентов медицинских, фармацевтических и биологических специальностей.
М.: Палея-М, 2001. — 133 с. Представленная рукопись отражает современные знания о метаболизме лекарственных препаратов, роли фармакокинетики и фармакогенетики в его изучении.
Уфа: БГМУ Минздрава России, 2020. — 195 с. — ISBN 978-5-907209-10-7. В пособии представлена современная классификация и краткая характеристика нежелательных лекарственных реакций. Освещены общие вопросы взаимодействия лекарственных средств. Подробно рассмотрена группа лекарственных препаратов — нестероидные противовоспалительные средства: принципы их классификации, механизм...
Учебник.— Харьков: Основа, 1996.— 288 с. Качество: хорошее, 300 дпи, текст нераспознан Один из первых отечественных учебников по данному вопросу. Содержит сведения о молекулярных основах процессов всасывания, распределения, связывания с белками, биотрансформации и выведения лекарственных веществ.
М.: Изд-во РАМН, 2003. — 208 с. — ISBN: 5-7901-0031-7. В книге подробно рассматриваются основные положения фармакокинетики и фармакодинамики, причины межиндивидуальной вариабельности фармакокинетических параметров, возможности ее описания в рамках популяционного моделирования. Дана оценка имеющимся подходам оптимизации процедуры терапевтического лекарственного мониторинга,...
Учебное пособие. — Хабаровск: Институт повышения квалификации специалистов здравоохранения, 2013. — 38 с. В учебном пособии представлены данные, касающиеся современной ингаляционной анестезии. В пособии описывается фармакокинетика и фармакодинамика используемых в настоящее время жидких и газообразных ингаляционных анестетиков. Учебное пособие предназначено для интернов,...
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