CRC Press, 2019. — 472 p. — ISBN 9781138336087. Mitochondria produce the chemical energy necessary for eukaryotic cell functions; hence mitochondria are an essential component of health, playing roles in both disease and aging. More than 80 human diseases and syndromes are associated with mitochondrial dysfunction; this book focuses upon diseases linked to these ubiquitous...
Springer, 2024. — 436 p. This book is a comprehensive guide to the pathology, underlying mechanisms, and treatment options for Alzheimer's disease (AD). The book starts with an introduction to the basic anatomy and physiology of the central nervous system, followed by an overview of the types, classifications, and basic concepts of neurodegenerative disorders. The epidemiology,...
Bates G. Huntington’s Disease Oxford University Press, 2014 - Medical - 502 pages This fourth edition of Huntington's Disease presents a comprehensive summary of the current knowledge of this disease, including the major scientific and clinical advances that have occurred since publication of the third edition in 2002. Completely updated and expanded, chapters in this volume...
4th edition. — Oxford University Press, 2014. — 1951 p. — (Oxford Monographs on Medical Genetics) — ISBN: 9780199370474 This fourth edition of Huntington's disease presents a comprehensive summary of the current knowledge of this disease, including the major scientific and clinical advances that have occurred since publication of the third edition in 2002. Completely updated...
New York, "Cambridge University Press", 2005. — 1009 p. Neurodegenerative diseases are among the major contributors to disabilityanddisease, with Alzheimer’sandParkinson’s diseases the most prevalent among many in this category. This major reference reviews the rapidly advancing knowledge of pathogenesis and treatment of neurodegenerative diseases in the context of...
New York: Springer, 2017. — 545 p. Alzheimer’s Disease: Insights from Genetic Mouse Models and Current Advances in Human IPSC-Derived Neurons Clinical Aspects of Alzheimer’s Disease Parkinson’s Disease: Basic Pathomechanisms and a Clinical Overview Huntington’s Disease: Pathogenic Mechanisms and Therapeutic Targets The Complexity of Clinical Huntington’s Disease: Developments...
Academic Press, 2007. — 435 p. Preface Dedication Cerebellum and Spinal Cord: Principles of Development, Anatomic Organization, and Functional Relevance Acquired Cerebellar Ataxias and Differential Diagnosis Multiple System Atrophy Clinical and Genetic Aspects of Spinocerebellar Ataxias with Emphasis on Polyglutamine Expansions Polyglutamine Ataxias: In Vitro and In Vivo Models...
Pan Stanford Publishing, 2012. — 432 p. This book describes the latest research on neurodegenerative disease and metal-binding proteins. It lays strong emphasis on biochemistry and cell biology. The diseases covered in the book include Parkinson's disease, Alzheimer's disease, prion disease, and ALS. The chapters separately examine such issues as mechanisms of metal binding,...
Healed and Whole Clinic, 2019. — 118 p. — ISBN 978-1733397315. The book begins with my own health journey through mitochondrial fatigue and how I overcame it with the functional medicine approach to diagnosis and treatment. The first two chapters discuss the basic science of the mitochondria and their involvement in cell defense, energy production, aging, and cancer. The...
ITAE, 2011. — 569 p. — ISBN 953307485X 9789533074856 9535143913 9789535143918. This book focuses on biological mechanisms, prevention, neuroprotection and even monitoring of disease progression. The book emphasizes the general biological processes of neurodegeneration in different neurodegenerative diseases. This book is suitable for different readers: college students can use...
2nd Edition. — John Wiley & Sons, Ltd, 2014. — 439 p. — ISBN: 1119977142. Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeostasis,...
Wiley, 2006. — 239 p.
Metals in Brain, Metal Transport, Storage and Homeostasis
Oxidative Stress and Redox-Active Metal Ions
Parkinson's Disease
Alzheomer's Disease
Huntington's Disease and Polyglutaminem Expansion Neurodegenerative Diseases
Friedrich's Ataxia and Diseases Associated with Expansion of Non-Coding Triplets
Creutzfeldt-Jacob and Other Prion Diseases...
Oxford: Oxford University Press, 2017. — 361 p. As the global population ages the impact of neurodegenerative diseases like Alzheimer's disease and Parkinson's disease are significant forces in shaping human health and quality of life in the 21st century. Insights into understanding these diseases, and knowing how to treat them are major frontiers of scientific research....
Berlin: Springer, 2011. — 171 p. The two greatest medical fears of the aging population are cancer and Alzheimer’s disease. Despite dramatic advances in understanding the molecular etiology of these disorders, therapeutic options for many patients with advanced disease have changed little and outcomes remain dismal. Paradoxically, recent findings suggest that some of the same...
Elsevier, 2017. — 264 p. — (Handbook of Clinical Neurology 142). — ISBN13: 978-0444636256. Wilson Disease provides a comprehensive guide on this inherited genetic disorder that has devastating consequences for both the liver and neurologic/psychiatric health. This disease is of increasing interest to neurologists, hepatologists, and geneticists, but when the disease is...
CRC Press, 2025. — 286 p. Neurodegenerative diseases, like Alzheimer's, Parkinson's, and Huntington's, cast a long shadow over millions of lives, stealing memories, independence, and futures. The rising tide of these age-related disorders threatens to overwhelm healthcare systems worldwide, prompting an urgent search for effective treatments. While current options offer...
Springer, 2016. — 158 p. — ISBN 978-3-319-23242-3. This timely book allows clinicians of the nervous system, who are increasingly confronted with degenerative and psychiatric diseases, to familiarize themselves with the cerebral amygdala and the anatomical structures involved in these pathologies. Its striking photos of cerebral sections and dissections should help MRI...
Berlin: Springer, 2010. — 213 p. The Role of Histone Deacetylases in Neurodegenerative Diseases and Small-Molecule Inhibitors as a Potential Therapeutic Approach Phosphodiesterase Inhibition to Target the Synaptic Dysfunction in Alzheimer’s Disease Glutamate and Neurodegenerative Disease Modulation of the Kynurenine Pathway for the Potential Treatment of Neurodegenerative...
Springer, Heidelberg Dordrecht London New York , Springer-Verlag Berlin Heidelberg, 2010. — 212 p. ISSN: 1862-2461 e-ISSN: 1862-247X, ISBN: 978-3-642-16757-7 e-ISBN: 978-3-642-16758-4. DOI 10.1007/978-3-642-16758-4. The Role of Histone Deacetylases in Neurodegenerative Diseases and Small-Molecule Inhibitors as a Potential Therapeutic Approach. Phosphodiesterase Inhibition to...
Singapore: Springer, 2022. — 227 p. This book provides a comprehensive summary of the latest knowledge regarding functional foods and new therapeutic strategies for neurodegenerative disorders through explaining specific mechanisms for natural remedies and functional foods as well as alternative treatment and supplementary approaches for neurodegenerative diseases. Many...
Elsevier, 2023. — 372 p. Foreword In Memoriam–Michael Parkinson Preface Contributors Basic science development Role of rodent models in advancing precision medicine for Parkinson's disease The allure and pitfalls of the prion-like aggregation in neurodegeneration The shift to a proteinopenia paradigm in neurodegeneration Disease mechanisms as subtypes: Lysosomal dysfunction in...
Elsevier, 2023. — 272 p. Precision Medicine in Neurodegenerative Disorders, Part One, Volume 192 in the Handbook of Clinical Neurology deals with the "Why" in the approach to slow the progression of accelerated brain aging. This volume is intended to provide a scholarly background on the framework, basic science and conceptual pitfalls related to disease-modifying efforts in...
Singapore: Springer Nature Singapore, 2024. — 1026 p. This Handbook discusses the pathology, etiology, pathogenesis, and therapeutic interventions of different neurodegenerative diseases. The initial section of the Handbook reviews the recent advances in understanding neurodegenerative diseases and the commonalities and differences between the major pathologies. The subsequent...
New York: Springer, 2010. — 420 p. Neurotraumatic (stroke, spinal cord trauma, and traumatic head injury) and neurodegenerative diseases (Alzheimer disease, Parkinson disease, Amyotrophic Lateral Sclerosis, Huntington disease, and prion disease) are afflicting aging Americans with increasing frequency. These diseases result in acute, as well as gradual and progressive...
Academic Press, 2021. — 388 p. — ISBN 978-0-12-821711-5. Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with...
Springer, 2015. — 277 p.
Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these...
2nd Edition. — Springer, 2018. — 412 p. — ISBN: 978-3-319-72937-4. This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, Lewy body dementia,Parkinson’s disease, amyotrophic lateral sclerosis, and additional less common neurodegenerative diseases. Both clinical and...
Springer, 2014. — 266 p. — ISBN: 978-1-4471-6380-0. This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments,...
Academic Press, 2022. — 235 p. — ISBN 978-0-12-820122-0. Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases elucidates elaborately the role of caspase enzymes implicated in the initiation of molecular events leading to neuronal apoptosis in the neurodegenerative disease. The book starts with introduction to neuropathology, neurogenetics, and epidemiology of...
Springer, 1995. — 690 p. — (Advances in Behavioral Biology. Vol. 44) — ISBN: 978-0-306-45004-4 This book represents the third in a series of International Conferences related to Alzheimer's (AD) and Parkinson's (PD) diseases. The first one took place in Eilat, Israel, in 1985; and the second one in Kyoto, Japan, in 1989. This book contains the full text of oral and poster...
2nd edition. — Springer, 2016. — 335 p. — ISBN: 978-3-319-23308-6 This new edition provides an accessible guide to the commonest neurodegenerative diseases, outlining the main clinical features, treatment options and outcomes of the conditions most frequently encountered in clinical practice.Beginning with an overview of the general principles that underlie degeneration, and the...
New York: Nova Science Publishers, 2020. — 162 p. Recent Developments in Neurodegeneration discusses the diverse functions of nitric oxide regarding redox regulation, the cellular energy pool, modifications in genetic material, neurogenesis, the effects on protein degradation mechanisms and functional consociation with glial cells. The authors consider the latest evidence that...
Nova Science Publishers, 2017. — 170 p. Huntington's disease (HD) is a progressive, fatal, dominant inherited neurodegenerative disorder caused by an unstable expansion of CAG repeats within the coding region of the IT15 gene that encodes for a protein called huntingtin (htt). The clinical hallmark of HD is a severe motor impairment, but cognitive and psychiatric symptoms are...
Springer, 2022. — 163 p. — ISBN 978-3-662-66368-4. This non-fiction book informs those interested in neuroscience and medicine about the latest findings on the therapy of neurodegeneration with a focus on Alzheimer's dementia and Parkinson's disease. What happens in the brain when we are ageing? How does neuronal cell death occur when we become forgetful? Which new therapies...
Royal Society of Chemistry, 2006. — 295 p. — ISBN: 978-0-85404-360-6. Bioinorganic chemistry has a cross disciplinary approach, applying the principles of chemistry to biological systems. Metallochemistry of Neurodegeneration: Biological, Chemical and Genetic Aspects discusses the rapidly developing area of metals in the nervous system and their role in neurodegenerative...
Springer, 2025. — 284 p. Foreword Preface Acknowledgments Editors and Contributors About the Editors Contributors List of Tables Foundations of Biomaterials: Types, Evolution, and Medical Applications Synthesis and Comprehensive Characterization of Neurocompatible Biomaterials Neuro-compatible Biomaterials: Pioneering Solutions for Brain and Nerve Disorders Advanced...
New York: Springer, 2017. — 153 p. This thesis covers various facets of brain image computing methods and illustrates the scientific understanding of neurodegenerative disorders based on four general aspects of multimodal neuroimaging computing: neuroimaging data pre-processing, brain feature modeling, pathological pattern analysis, and translational model development. It...
Springer, 2013. — 401 p. — (Advances in Predictive, Preventive and Personalised Medicine) — ISBN: 978-94-007-5865-0 Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future Recent advances in ALS research Recent advances in ALS research Predictive, Preventive and Personalised Medicine in aging macular degeneration Advances in Multiple Sclerosis...
Springer, 2024. — 195 p. This book delves into the correlation between different enzymes and neurodegenerative disorders. It investigates the intricate processes that contribute to the decline of cognitive functions, memory impairment, and other incapacitating symptoms of Alzheimer's disease. The book examines the roles of diverse enzymes in Amyotrophic Lateral Sclerosis and...
Humana Press, 2001. — 296 p. Recent scientific advances have dramatically expanded our understanding of the molecular, genetic, and environmental factors that either cause or contribute to a wide variety of age-related neurodegenerative disorders. In Pathogenesis of Neurodegenerative Disorders, leading experts detail the cellular and molecular cascades that cause selective...
Published by The Royal Society of Chemistry (RSC) Publishing, Cambridge, 2011. — 270 p. — ISBN: 978-1-84973-050-1. серия RSC Drug Discovery Since Alois Alzheimer described the results of his postmortem studies in 1906, significant strides have been made in understanding the pathogenesis of neurodegenerative diseases. Substantial evidence has accumulated indicating that diverse...
Sharjah: Bentham Science Publishers, 2021. — 232 p. Researchers have tried various effective treatments that prevent the progressive neurodegeneration of neurons within the brain. Parkinson’s disease (PD), Alzheimer’s disease (AD), and Multiple sclerosis (MS) are some of the most common neurodegenerative diseases (NDDs). Recent Advances in the Treatment of Neurodegenerative...
Springer, 2015. — 402 p. — (Current Topics in Behavioral Neurosciences 22) — ISBN: 978-3-662-46343-7 Motor dysfunction and cognitive impairment are major symptoms in both Huntington’s Disease (HD) and Parkinson’s Disease (PD). A breakthrough in HD research was the identification of the gene that causes this devastating monogenetic illness. Similarly, several genes were found to...
Humana Press, 2022. — 1722 p. — (Neuromethods 173). — ISBN 978-1-0716-1712-0. This volume presents recent data on the latest achievements in new and emerging technologies for biomarkers and for innovations in their assessment. The chapters cover topics such as activation of microglia and macrophages in neurodegenerative diseases; oxidative stress and cellular dysfunction in...
Humana Press, 2022. — 566 p. — (Neuromethods 173). — ISBN 978-1-0716-1711-3. This volume presents recent data on the latest achievements in new and emerging technologies for biomarkers and for innovations in their assessment. The chapters cover topics such as activation of microglia and macrophages in neurodegenerative diseases; oxidative stress and cellular dysfunction in...
Springer, 2023. — 483 p. — ISBN 978-981-99-7730-7. This book explores the potential benefits of turmeric, and specifically curcumin, in the treatment and prevention of neurodegenerative diseases. The book covers various aspects of turmeric, including its traditional use in Ayurveda and Chinese medicine, secondary metabolites, curcuminoids, and sesquiterpenoids found in...
Springer, 2023. — 483 p. — ISBN 978-981-99-7731-4. This book explores the potential benefits of turmeric, and specifically curcumin, in the treatment and prevention of neurodegenerative diseases. The book covers various aspects of turmeric, including its traditional use in Ayurveda and Chinese medicine, secondary metabolites, curcuminoids, and sesquiterpenoids found in...
2nd edition. — Springer, 2016. — 379 p. — ISBN: 978-3-319-28635-8 This second edition brings together up-to-date contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease and multiple sclerosis. The reader is...
Humana, 2019. — 348 p. — (Current Clinical Neurology). — ISBN10: 3319978969, 13 978-3319978963. This case-based text provides treatment approaches to common and uncommon movement disorders. The first two parts of the book are devoted to the wide spectrum of motor and non-motor problems encountered in caring for people with Parkinson's disease, as well as Parkinsonian syndromes....
Boca Raton: CRC Press, 2024. — 255 p. This reference book provides a comprehensive overview of models and therapeutic approaches against neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. It explores models based on the chemical, induced, cellular, genetic, transgenic, and 3D organoid...
New York: Wiley-Blackwell, 2017. — 343 p. This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject. Presents a clinically oriented guide to the diseases caused by neurodegeneration Templated chapters combine clinical and research information on neurodegenerative...
Wiley-Blackwell, 2017. — 343 p. — ISBN10: 0470672684. — ISBN13: 978-0470672686. This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject. Presents a clinically oriented guide to the diseases caused by neurodegeneration Templated chapters combine clinical and...
Nova Science Publishers, 2017. — 175 p. Neurodegenerative diseases are widespread disorders, with prevalence increasing with age. The first chapter of this book discusses autophagy, a cellular tool for the elimination of proteins that accumulate in neurodegenerative disorders and have pathogenetic significance. Parkinsons disease (PD) is one of the most common degenerative...
CRC Press, 2024. — 278 p. This book explores the pivotal role of synaptic plasticity in the pathogenesis, progression, and potential treatment of neurodegenerative disorders. The initial chapter provides an in-depth understanding of the complexity and impact of neurodegenerative conditions. It discusses the association of mitochondrial dysfunction, epigenetic influences, and...
Springer, 2019. — 1138 p. — ISBN: 978-981-13-0944-1 This book, written by a leading panel of experts in the field of neurosciences, provides a comprehensive overview of the pathology of neurodegenerative diseases as well as the preventive measures. Prevention is important due to the lack of early diagnostic markers and the limitations/ problems of treating neurodegenerative...
Springer, 2019. — 302 p. — ISBN: 978-981-13-0943-4 This book, written by a leading panel of experts in the field of neurosciences, provides a comprehensive overview of the pathology of neurodegenerative diseases as well as the preventive measures. Prevention is important due to the lack of early diagnostic markers and the limitations/ problems of treating neurodegenerative...
Springer, 2023. — 476 p. — (Contemporary Clinical Neuroscience). — ISBN 978-3-031-32814-5. Huntington’s disease (HD) is a fatal, inherited, neurodegenerative disorder, characterized by chorea, motor instabilities, psychiatric manifestations and cognitive decline. Early genetic testing provides an opportunity for clinical interventions aimed at delaying onset and/or slowing...
ITexLi, 2021. — 152 p. — ISBN 1838801502 9781838801502 1838801499 9781838801496 1838803602 9781838803605. The book is intended to serve as a source to aid clinicians and researchers in the field, and also life science readers to increase their understanding and awareness of the clinical correlations, genetic aspects, neuropathological findings, and current therapeutic...
Singapore: Springer, 2019. — 407 p. This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. Neuroglia are the most abundant cells in the nervous system and consist of several distinct cell types, such as astrocytes, oligodendrocytes,and microglia. Accumulating evidence suggests that neuroglia participate in the neurodegenerative...
Cham: Springer, 2023. — 423 p. The 4th World Congress on Genetics, Geriatrics, and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific...
The Royal Society of Chemistry, UK, 2013. — 234 p. — (RSC Metallobiology Series No.1) — ISBN: 1849735883 The increase in the ageing population will ultimately lead to a higher number of patients presenting with dementia as well as neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. As neurological, psychiatric diseases and sensory deficits will...
American Psychiatric Association, 2012. — 471 p. — ISBN: 978-1-58562-422-5 In Clinical Manual of Alzheimer Disease and Other Dementias, practicing psychiatrists and neurologists provide essential input into neuropsychiatric assessment and the diagnosis and treatment of a wide range of neuropsychiatric conditions, including Alzheimer disease and traumatic brain injury. The...
Academic Press, 2018. — 545 p. — ISBN 978-0128113042. The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by...
Hauppauge: Nova Science Publishers, Incorporated, 2006. — 283 p. The brain has long been considered an immune privileged organ, meaning that inflammatory cells are excluded due to a relatively impenetrable blood brain barrier (BBB). However, this is not to say that the central nervous system is incapable of eliciting immune responses, as resident inflammatory cells exist within...
Cambridge: Published by The Royal Society of Chemistry, 2011. — 290 p. — (RSC Drug Discovery). — ISBN: 978-1-84973-184-3. In recent years, medical developments have resulted in an increase in human life expectancy. Some developed countries now have a larger population of individuals aged over 64 than those under 14. One consequence of the ageing population is a higher incidence...
Учебное пособие. — Уфа: БГМУ Минздрава России, 2018. — 96 с. Учебное пособие подготовлено в соответствии с требованиями ФГОС ВО по специальности «Лечебное дело», ООП ВО по направлению подготовки специальности «Лечебное дело», изучения дисциплины «Неврология, медицинская генетика» на основании рабочей программы (2016 г.) и действующего учебного плана (2017 г.). Освещены вопросы,...
Томск : Изд-во СибГМУ, 2021. — 101 с. Представлен материал, отражающий современные клинико-патогенетические представления о механизмах нейродегенеративных заболеваний в неврологии. В пособии изложены современные представления об этиологии, патогенезе, классификации и дифференциальной диагностике заболеваний, сопровождающихся синдромом паркинсонизма. Приведены ситуационные...
М.: Фолиант, 2013. — 200 с. В руководстве представлены сведения о группе дегенеративных заболеваний нервной системы, встречающихся в клинической практике врача-невролога. Обсуждаются современные данные по эпидемиологии, этиологии, патогенезу, клинической картине, диагностике, дифференциальной диагностике, лечению и прогнозу. Для неврологов и врачей других специальностей,...
Учебное пособие. — Иркутск: Мегапринт, 2019. — 120 с. — ISBN: 978-5-907095-83-0. В учебном пособии отражены основные вопросы этиологии, клинической картины, дифференциальной диагностики и лечения нейродегенеративных заболеваний с преимущественным поражением экстрапирамидной системы. Приведены современные критерии диагностики болезни Паркинсона, прогрессирующего надъядерного...
Монография. — М.: Московский педагогический государственный университет, 2017. — 160 с. — ISBN: 978-5-4263-0553-3. Клеточные технологии произвели революцию в области медицины за последние несколько десятилетий. В последние годы трансплантация клеток в головной и/или спинной мозг исследовалась как потенциальное средство лечения ряда заболеваний центральной нервной системы, таких...
Учеб. пособие. М.: РУДН, 2008. – 188 с. В учебном пособии рассматривается современная приоритетно российская остеогенная концепция нейроортопедических заболеваний, разработанная в РУДН. На основе остеогенной концепции дается описание патогенетического метода внутрикостных блокад для лечения болевых синдромов, обусловленных дегенеративно-дистрофическим поражением...
Комментарии