Buckingham Lela (ed.) Molecular Diagnostics: Fundamentals, Methods, and Clinical Applications

3rd edition. — F. A. Davis Company, 2019. — 583 p. — ISBN: 978-0-8036-6829-4Molecular diagnostics continues to grow in importance in the clinical laboratory. This respected text will prepare your students with a grounding in the fundamental principles of molecular biology. current methods, and their clinical applications.With a focus on the application of molecular concepts to diagnostic purposes, the text explains and illustrate the use and interpretation of molecular-based assays in patient care. Now with an expanded discussion of nucleic acid sequencing, with added emphasis on next generation sequencing (NGS), and updated coverage of proteomics and mass spectrometry applications, your students will have the most current information available today.Fundamentals of Molecular Biology: An Overview
Nucleic Acids and Proteins
Gene Expression and Epigenetics
Common Techniques in Molecular Biology
Nucleic Acid Extraction Methods
Resolution and Detection of Nucleic Acids
Analysis and Characterization of Nucleic Acids and Proteins
Nucleic Acid Amplification
Chromosomal Structure and Chromosomal Mutations
Gene Mutations
DNA Sequencing
Techniques in the Clinical Laboratory
DNA Polymorphisms and Human Identification
Detection and Identification of Microorganisms
Molecular Detection of Inherited Diseases
Molecular Oncology
DNA-Based Tissue Typing
Quality Assurance and Quality Control in the Molecular Laboratory